Prostate Cancer Gleason Score

Prostate Cancer Gleason ScoreProstate cancer Gleason score is considered as the most common grading system to determine one’s prostate cancer staging. This score is to classify how serious and aggressive is the cancer cells invading the prostate. Yet, Gleason score is only eligible for the most common prostate cancer or adenocarcinoma.


Adenocarcinoma is one type of cancer which is produced in mucus-secreting glands that are located in various parts of our body. This cancer can occur in lung, prostate, pancreatic, esophageal and colorectal.

In the case of prostate cancer, adenocarcinoma occurs in 95% happenings, so the chance of having this type of cancer is considerably high.

Adenocarcinoma can be diagnosed through several tests. The first possible test is through biopsy. In simple words, biopsy is when the abnormal tissue contained by a part of your body is removed in order to get more elaborate examination under the microscope. Later, cancer cells will be determined from this process.

Another method is by Computerized Tomography or CT scan. Through this procedure, an x-ray which is controlled by the computer will be used to analyze some parts of your body to find out whether abnormal tissue is present or not.

Lastly, Magnetic Resonance Imaging or MRI can also be used to diagnose the cancer cells. This method uses radiofrequency to produce images of several different parts of your body.

Prostate cancer Gleason score has close connection with the biopsy. The result of biopsy test is subsequently analyzed and classified in order to get clearer explanation about how aggressive one’s prostate cancer has grown.


Before we continue the explanation to the system of this Gleason score, you might want to know that the system was established by Dr. Donald F. Gleason who is a pathologist in Minnesota.

Gleason score is a system which measure the level or aggressiveness of one’s prostate cancer with a scale. The scale itself is maintained to be from 1 to 5. You might be able to guess that the lower the number, the less potential of you having abnormal cells. It means that your prostate cancer might be in a low-grade. This scale is differentiated by the patterns as well as the growth of the cells. In addition, the number of 1 to 5 actually represents different specific patterns of the tissue being removed through biopsy and examined under a microscope. This is how the pathologists are able to work on the classification.

The next procedure is checking up the biopsy’s result. This result will be used to examine the two grade patterns in the tumor. The scale of 1 to 5 will be given to each of these grades. Later, the number of the two grade patterns are summed up to get the final Gleason score.

Therefore, you can count by yourselves that the minimum total of Gleason score is 6 while the maximum is 10. Again, this scale, from 6 to 10 will be used to decide in which stage your prostate cancer is. The less number your result shows, the less aggressive the prostate cancer.